A MODIFIED DELPHI APPROACH TO DEVELOP A TRIAL PROTOCOL FOR ANTIBIOTIC DE-ESCALATION IN PATIENTS WITH SUSPECTED SEPSIS

A modified Delphi approach to develop a trial protocol for antibiotic de-escalation in patients with suspected sepsis

Abstract Background: Early administration of antibiotics in sepsis is associated with improved patient outcomes, but safe and generalizable approaches to de-escalate or discontinue antibiotics after suspected sepsis events are unknown.Methods: We used a modified Delphi approach to identify safety criteria for an opt-out protocol Zodiac T5 Duo Parts

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